Listning ID 160931 Description
Botulinum toxin type A blocks peripheral release of acetylcholine at presynaptic cholinergic nerve endings by splitting SNAP-25, an integral part of the binding and release of acetylcholine vesicles located in nerve endings. After injection occurs initial rapid binding of the toxin to surface receptors of certain cells. After that there is a transfer of the toxin through the membrane of the blood plasma through receptor-mediated endocytosis. Additional information
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